Common Questions and Answers about Clindamycin weight gain benzaclin The Doctor wanted her to start on Ortho Tri-cyclen but she did not want to go that route yet because she is afraid it would make her gain weight. The information reflected here is dependent upon the correct functioning of our algorithm. From time-to-time, our system might experience bugs or glitches that affect the accuracy or correct application of mathematical algorithms. Clindamycin is an antibiotic useful for the treatment of a number of bacterial infections. This includes middle ear infections, bone or joint infections, pelvic inflammatory disease, strep throat, pneumonia, and endocarditis among others. Mechanism of Action. Clindamycin works by stopping the pathogenic bacteria that are the cause of the infection from multiplying. In addition, it exerts an extended postantibiotic effect against some strains of pathogenic bacteria. Along with its needed effects, clindamycin topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. clindamycin and alcohol : Getting Plenty Of Sleep Is Essential To weight loss challenge I recently had a root canal and was given a prescription of Clindamycin. I'd been losing weight continually since April. I went from 184.6 to 149 pounds without and special diet or exercise. Extreme diarrhea and weight loss are common symptoms of SIBO. Any of the antibiotics listed above stop the diarrhea and weight loss. I'm going to take my probiotics and antibiotics the same day, spaced several hours apart. Check with your doctor immediately if any of the following side effects occur while taking clindamycin: Rare. Cracks in the skin; loss of heat from the body Clindamycin may cause fever, headache, back pain or sore throat. Kidney or urinary tract problems such as a decrease in urine production, urinary tract infection or protein in the urine may develop.